Harnessing Next-Generation Sequence Technology to Elucidate Healthcare-Associated Infection Transmission Pathways

TERAFLUX: Harnessing dataflow in next generation teradevices

The improvements in semiconductor technologies are gradually enabling extreme-scale systems such as teradevices (i.e., chips composed by 1000 billion of transistors), most likely by 2020. Three major challenges have been identified: programmability, manageable architecture design, and reliability. TERAFLUX is a Future and Emerging Technology (FET) large-scale project funded by the European Unio...

Harnessing virtual machines to simplify next-generation DNA sequencing analysis

MOTIVATION The growth of next-generation sequencing (NGS) has not only dramatically accelerated the pace of research in the field of genomics, but it has also opened the door to personalized medicine and diagnostics. The resulting flood of data has led to the rapid development of large numbers of bioinformatic tools for data analysis, creating a challenging situation for researchers when choosi...

An Introduction to Next-Generation Sequencing Technology

An Introduction to Next-Generation Sequencing Technology Welcome to Next-Generation Sequencing

Deciphering DNA sequences is essential for virtually all branches of biological research. With the advent of capillary electrophoresis (CE)-based Sanger sequencing, scientists gained the ability to elucidate genetic information from any given biological system. This technology has become widely adopted in laboratories around the world, yet has always been hampered by inherent limitations in thr...

An Introduction to Next-Generation Sequencing Technology Welcome to Next-Generation Sequencing

Deciphering DNA sequences is essential for virtually all branches of biological research. With the advent of capillary electrophoresis (CE)-based Sanger sequencing, scientists gained the ability to elucidate genetic information from any given biological system. This technology has become widely adopted in laboratories around the world, yet has always been hampered by inherent limitations in thr...